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So far – So good!

You appear to meet the basic requirements for this COVID-19 Vaccine study. Please enter your information below to find a study location near you. Once you select a site, the research study staff will contact you to see if you qualify to enroll.

So far – So good!

Your child appears to meet the basic requirements for this COVID-19 vaccine study. However, only the research study staff can fully determine if your child qualifies to enroll. Please enter your contact information and select “Find a Site” to see if there is a study site enrolling in your area.

Note: Parents and guardians should input their contact information, not their child’s.

So far – So good!

Your adolescent appears to meet the basic requirements for this COVID-19 vaccine study. However, only the research study staff can fully determine if your adolescent qualifies to enroll. Please enter your contact information and select “Find a Site” to see if there is a study site enrolling in your area.

Note: Parents and guardians should input their contact information, not their adolescent’s.

Sorry, you are not eligible or we may not be recruiting your age group at this time...

Thank you so much for your interest in this COVID-19 vaccine study and for answering our questions. Contact your healthcare provider if you have any medical questions. Also, please consider entering your information below to be contacted about future clinical research opportunities.

Sorry, you are not eligible at this time...

Thank you for your interest in this COVID-19 vaccine study and for answering our questions. Contact your healthcare provider if you have any medical questions. Also, please consider entering your information below to be contacted about future clinical research opportunities.

Sorry, your adolescent is not eligible at this time...

Thank you for your interest in this COVID-19 vaccine study and for answering our questions. Contact your healthcare provider if you have any medical questions. Also, please consider entering your information below to be contacted about future clinical research opportunities.

A Targeted Approach Against COVID-19

Learn more about the Pfizer & BioNTech COVID-19 Omicron Variant BA.4/BA.5 Targeted Vaccine Study for previously vaccinated and boosted people.

Please note: we are currently recruiting participants ages 56 years and older.

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Question 1 of 2

Are you at least 56 years old?

Question 2 of 2

Have you received only 3 prior doses of the Pfizer & BioNTech COMIRNATY® COVID-19 vaccine, with the third dose occurring 5 to 12 months ago?

Please select a full valid address.

Choose a Location

Please select a research site near you. If you don't see a site near you, then select "The sites listed here are not convenient for me." and a study representative will contact you if a site opens in your area.

The sites listed here are not convenient for me.

About The Study

This study is evaluating the safety, tolerability, and immune response generated by a single dose of a redesigned bivalent Omicron BA.4/BA.5 study vaccine in children 12-17 years old and adults who have received only 3 prior doses of the Pfizer & BioNTech COMIRNATY® vaccine. About 500 participants will be enrolled in the United States.

We are currently recruiting adults 56 years and older.

An Important Contribution

Receiving a COVID-19 vaccine and booster is still the best strategy for protecting yourself and others from serious illness. However, the level of protection against COVID-19 has been shown to decrease with time, just like it does after natural infection. For this reason, researchers are evaluating if a redesigned version of an investigational vaccine may improve and extend the immune response, particularly against BA.4 and BA.5, two new versions of the Omicron variant that are now responsible for the majority of COVID-19 cases in the United States.

By choosing to volunteer, you will represent others like you – in age, gender, race, ethnicity, and from communities like yours. Including people from all backgrounds will improve the effectiveness of the COVID-19 vaccine for everyone.

Joining a clinical trial is an important and personal decision. Thank you for considering this study.

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What to Expect

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This study does not include a placebo (injection with no active ingredient). All participants will receive a single dose of the study vaccine. Adult participants will be randomly assigned to receive 1 of 2 possible dose levels of the study vaccine. Doses will be given as an injection in the upper arm.

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Participants will be enrolled in the study for about 6 months and will need to attend at least 5 study visits during this time.

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Participants may be reimbursed for expenses and time related to completing study activities.

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